GLUT-1 (Tumor Progression and Mesothelioma Marker)(rGLUT1/2476), 0.2mg/mL

Primary

Antibodies

Purified, with BSA

Store at 2 to 8°C|Protect fluorescent conjugates from light

Recognizes a protein of 55 kDa, which is identified as GLUT-1. Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut-1 to Glut-12. Glut-1 is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung, bladder and mesothelioma. Glut-1 is a sensitive and specific marker for the differentiation of malignant mesothelioma (positive) from reactive mesothelium (negative). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

2 years

41116161

PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)

PBS, 0.05% BSA, 0.05% azide

Recombinant fragment of human GLUT1 protein (around aa 203-305) (exact sequence is proprietary)

For research use only (RUO)

473721

Plasma membrane

GLUT-1