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Anti-TMPRSS2 Rabbit Monoclonal Antibody

Anti-TMPRSS2 Rabbit Monoclonal Antibody

Item no.	BOS-M00666
Manufacturer	Boster
Amount	100 ul/vial
Quantity options	100 ul/vial 30 ul
Category	Oncology Infectious Diseases Viral Infections Coronavirus (COVID-19) Antibodies By Cell Type Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies Immunochemistry
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, FC, IF, IHC, ICC
Clone	23T34
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<10 pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Matrix metalloproteinase-14,MMP-14,3.4.24.80,MMP-X1,Membrane-type matrix metalloproteinase 1,MT-MMP 1,MTMMP1,Membrane-type-1 matrix metalloproteinase,MT1-MMP,MT1MMP,MMP14
Available
Manufacturer - Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	54 kDa
Calculated Molecular weight	65894 MW
Clonality	Monoclonal
Application Details	WB 1:500-2000 IHC 1:50-200 ICC/IF 1:50-200 FC 1:60
Gene Name	TMPRSS2
Gene Full Name	Matrix metalloproteinase-14
Immunogen	A synthesized peptide derived from human TMPRSS2
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	0.5mg/ml
Manufacturer - Research Category	Apoptosis, Cancer, Cell Biology, Cell Cycle, Cell Cycle Inhibitors, Cell Death, Nucleus, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, SCF Complex E3 Ligase, Ubiquitin E3 Enzymes
Protein Name	T-cell surface glycoprotein CD4
Protein Function	Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro- MMP2.
Subcellular Localization	Membrane; Single-pass type I membrane protein. Melanosome. Cytoplasm. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Forms a complex with BST2 and localizes to the cytoplasm.
Description	Boster Bio Anti-TMPRSS2 Rabbit Monoclonal Antibody catalog # M00666. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in stromal cells of colon, breast, and head and neck. Expressed in lung tumors.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M00666-datasheet.pdf

BOS-M00666-safety-datasheet.pdf