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Eg5 (phospho-T926) polyclonal antibody

Eg5 (phospho-T926) polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neural Signaling Antibodies Cell Biology Cytoskeleton Western Blot Motor proteins Primary Antibodies
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Applications	WB
Amount	50ul
Host	Rabbit
Item no.	BS4428-50
Targets	KIF11
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	P52732
Application_all	WB: 1:500ca.1:1000
Background	Eg5 (also called kinesin-like protein 11 or Kif11) belongs to the kinesin-like family of motor proteins important in chromosome positioning, centrosome separation, and mitotic spindle formation. Phosphorylation of Eg5 by mitotic kinases regulates its activity by modulating its association with microtubules. Because anti-mitotic chemotherapeutic drugs, such as taxanes, target microtubules and have pleiotropic and sometimes toxic effects, drugs that target microtubule-associated proteins such as Eg5 are currently in development.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage And Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	p-Eg5 (T926) pAb detects endogenous levels of Eg5 protein only when phosphorylated at Thr926.
BiowMW	ca. 120 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Synthetic phosphopeptide derived from human Eg5 around the phosphorylation site of Threonine 926

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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