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DKK3 polyclonal antibody

DKK3 polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neural Lineage Markers Antibodies Western Blot Primary Antibodies Glial Cell Markers
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Applications	WB
Amount	100ul
Host	Rabbit
Item no.	BS62351-100
Targets	DKK3
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	Q9UBP4
Application_all	WB: 1:500ca.1:1000 IHC: 1:50ca.1:200
Background	Dickkopf-related protein 3, antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage And Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	DKK3 polyclonal antibody detects endogenous levels of DKK3 protein.
BiowMW	ca. 55 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Synthetic peptide, corresponding to Human DKK3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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