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FAIM2 polyclonal antibody

FAIM2 polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Cell Biology Cell Status Apoptosis Western Blot Enzymes Fatty Acid Synthesis Primary Antibodies
Type	Antibody Primary
Specific against	Human, Mouse
Applications	WB
Amount	100ul
Host	Rabbit
Item no.	BS62375-100
Targets	FASN
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	Q9BWQ8
Application_all	WB: 1:500ca.1:1000 IHC: 1:50ca.1:200
Background	FAIM2 (fas apoptotic inhibitory molecule 2), also known as LFG (protein lifeguard), TMBIM2 (transmembrane BAX inhibitor motif-containing protein 2) and NMP35 (neural membrane protein 35), is a 316 amino acid multipass membrane protein that uniquely protects cells from Fas-induced apoptosis. Though widely expressed, FAIM2 expression is highest in hippocampus. FAIM2 contains seven transmembrane domains and resembles Bax Inhibitor-1, another anti-apoptotic protein. Overexpression of FAIM2 results in decreased caspase activation and reduced incidence of programmed cell death. Though mechanistically related to the Fas signal, FAIM2 does not protect cells from apoptosis that is mediated by TNF-alpha signaling. FAIM2 specifically regulates apoptosis by binding to the FAS receptor.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage And Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	FAIM2 polyclonal antibody detects endogenous levels of FAIM2 protein.
BiowMW	ca. 36 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Synthetic peptide, corresponding to Human FAIM2.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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