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CD91 (Phospho-S4520) polyclonal antibody

CD91 (Phospho-S4520) polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neural Lineage Markers Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Aging & Neurological Disorders Antibodies Obesity Western Blot Lipoprotein Receptors & Associated Proteins Primary Antibodies Adhesion Molecule Markers
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Applications	WB
Amount	50ul
Host	Rabbit
Item no.	BS64564-50
Targets	LRP1;;MSI1
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	Q07954
Application_all	WB: 1:500ca.1:1000 IHC: 1:50ca.1:200
Background	Musashi1 (Msi1) is an RNA-binding protein expressed in neural progenitor cells and neural stem cells. Msi1 is the mammalian homolog of Drosophila Musashi. The gene encoding human Msi1 encodes a 362 amino acid protein. In murine embryonic neural progenitor cells, Msi1 localizes to the cytoplasm and is downregulated during differentiation. Msi1 binds to NUMB, which encodes a membrane-associated antagonist of Notch signaling. Msi1 appears to function in the proliferation and maintenance of stem cell populations of the central nervous system. In addition to its usefulness as a marker for neural progenitor cells in normal human brains, Msi1 is also a marker for human gliomas. In rats, Msi1 is expressed in Sertoli cells of the testis and granulosa cells of the ovary.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage And Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	CD91 (Phospho-S4520) polyclonal antibody detects endogenous levels of CD91 protein only when phosphorylated at Ser4520.
BiowMW	ca. 85 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Synthetic phosphopeptide derived from human CD91 around the phosphorylation site of Serine 4520.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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