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MRTF-A polyclonal antibody

MRTF-A polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Applications	WB
Amount	50ul
Host	Rabbit
Item no.	BS72392-50
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	Q969V6
Application_all	WB 1:500 - 1:2000
Background	Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF regulates the transient response of several muscle genes in response to growth factors and recruits accessory myogenic factors to activate these muscle genes. SRF is required for the formation of vertebrate mesoderm leading to the origin of the cardiovascular system. Myocardin, in association with SRF in cardiac muscle cells, activates cardiac muscle promoters. Myocardin-related transcription factor A (MRTF-A), also known as MKL1, interacts with SRF and stimulates its transcriptional activity.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage And Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	MRTF-A polyclonal antibody detects endogenous levels of MRTF-A protein.
BiowMW	ca. 145 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Recombinant protein of human MKL1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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