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LRRK2 polyclonal antibody

LRRK2 polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neuroinflammation Neural Mitochondrial Function Molecular Targets for Neuroscience Antibodies Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Primary
Specific against	Human
Applications	WB, IF
Amount	100ul
Host	Rabbit
Item no.	BS72632-100
Targets	LRRK2
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	Q5S007
Application_all	WB 1:500 - 1:2000 IF 1:50 - 1:100
Background	This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage And Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	LRRK2 polyclonal antibody detects endogenous levels of LRRK2 protein.
BiowMW	ca. 286 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Recombinant protein of human LRRK2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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