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Histone H4 (Acetyl-K16) polyclonal antibody

Histone H4 (Acetyl-K16) polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neural Epigenetics Antibodies Western Blot Immunofluorescence Primary Antibodies CHiP
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Applications	WB, IF, CHIP
Amount	50ul
Host	Rabbit
Item no.	BS74024-50
Targets	CCDC6;;H4C1
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	P62805
Application_all	WB 1:500 - 1:2000 IF 1:50 - 1:200 ChIP 1:50 - 1:200
Background	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage And Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	Histone H4 (Acetyl-K16) polyclonal antibody detects endogenous levels of Histone H4 protein only when acetylated at K16.
BiowMW	ca. 13 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	A synthetic acetylated peptide corresponding to residues surrounding Lysine 16 of human Histone H4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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