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ApoER2 polyclonal antibody

ApoER2 polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Obesity Flow Cytometry Immunohistochemistry Western Blot Immunocytochemistry Lipoprotein Receptors & Associated Proteins Lipid & Fatty Acid Transport Primary Antibodies
Type	Antibody Primary
Specific against	Human, Mouse
Applications	WB, FC, IHC, ICC
Amount	100ul
Host	Rabbit
Item no.	BS90079-100
Targets	APOE;;LDLR;;LRP1
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	Q14114(Human) Q924X6(Mouse)
Application_all	WB:1:500-1:1, 000 ICC:1:50-1:200 IHC:1:50 FC:1:50-1:100
Background	ApoER2 (apolipoprotein E receptor 2), also designated LRP8, is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. ApoER2 is expressed in brain and placenta and has several splice variants. ApoER2 is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	Protein affinity purified.
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Specificity	ApoER2 polyclonal antibody detects endogenous levels of ApoER2 protein.
BiowMW	77 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Recombinant protein within human ApoER2 500-750 aa.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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