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BAF57 polyclonal antibody

BAF57 polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Antibodies Cell Biology Cell Movement Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies Cell Migration & Invasion
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Applications	WB, IF, IP, IHC, ICC
Amount	50ul
Host	Rabbit
Item no.	BS90116-50
Targets	SMARCA4;;SMARCE1
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	Q969G3(Human) O54941(Mouse) Q56A18(Rat)
Application_all	WB:1:500-1:2, 000 ICC/IF:1:50-1:200 IHC:1:50-1:200 IP:1:50-1:200
Background	The SWI/SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF1 or SNF2alpha) and Brg-1 (also designated SNF2 or SNF2beta) are the ATPase subunits of the mammalian SWI/SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI/SNF complex. In higher eukaryotes, BAF57 is also a critical component of the SWI/ SNF complex. BAF57 contains a high-mobility-group (HMG) domain adjacent to a kinesin-like region and is a DNA-binding subunit of the SWI/SNF complex. The human BAF57 gene maps within the q12-25 region of chromosome 17, a gene-rich area implicated in breast and ovarian cancers.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	ProA affinity purified
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Specificity	BAF57 polyclonal antibody detects endogenous levels of BAF57 protein.
BiowMW	47 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Recombinant protein within human BAF57 aa 1-200.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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