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CD11b polyclonal antibody

CD11b polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neural Lineage Markers Neuroinflammation Aging & Neurological Disorders Neural Adhesion Molecules Antibodies Cell Biology Cell Movement Cell Adhesion Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies Oligodendrocyte Markers
Type	Antibody Primary
Specific against	Human
Applications	WB, FC, IF, IP, IHC, ICC
Amount	100ul
Host	Rabbit
Item no.	BS90210-100
Targets	C3 ;;CD35;;ITGA3;;ITGA4;;ITGAM
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	P11215(Human)
Application_all	WB:1:500-1:1, 000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100
Background	Integrin alphaM, also designated complement component receptor-3 alpha, CD11b (p170), macrophage antigen a polypeptide, cell surface glycoprotein Mac-1 a subunit, MAC1A, MO1A and ITGAM) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin alphaM combines with the Integrin beta2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin alphaM/beta2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	ProA affinity purified
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Specificity	CD11b polyclonal antibody detects endogenous levels of CD11b protein.
BiowMW	170 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Recombinant protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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