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c-Fos polyclonal antibody

c-Fos polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neural Lineage Markers Neural Transcription Factors Molecular Targets for Neuroscience Neural Signaling Antibodies Cell Biology Cell Status Flow Cytometry Western Blot Senescence Primary Antibodies Neuronal Cell Markers
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Applications	WB, FC
Amount	100ul
Host	Rabbit
Item no.	BS90295-100
Targets	FOS ;; RB1 ;;FOSB
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	P01100(Human) P01101(Mouse) P12841(Rat)
Application_all	WB:1:1, 000 FC:1:50-1:100
Background	The c-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phospho-protein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. Functional homologs of c-Fos include the Fra-1, Fra-2 and Fos B genes. In addition, selected ATF/CREB family members can form leucine zipper dimers with Fos and Jun. Different dimers exhibit differential specificity and affinity for AP-1 and CRE sites.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	ProA affinity purified
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Specificity	c-Fos polyclonal antibody detects endogenous levels of c-Fos protein.
BiowMW	62 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	recombinant protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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