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CFTR polyclonal antibody

CFTR polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Antibodies Flow Cytometry Immunohistochemistry Western Blot Immunocytochemistry Primary Antibodies
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Applications	WB, FC, IHC, ICC
Amount	50ul
Host	Rabbit
Item no.	BS90296-50
Targets	TP53
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	P13569(Human) P26361(Mouse) P34158(Rat)
Application_all	WB:1:500-1:1, 000 ICC:1:50-1:500 IHC:1:50-1:20 FC:1:50-1:100
Background	EEpithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Exerts its function also by modulating the activity of other ion channels and transporters . Plays an important role in airway fluid homeostasis . Contributes to the regulation of the pH and the ion content of the airway surface fluid layer and thereby plays an important role in defense against pathogens. Modulates the activity of the epithelial sodium channel (ENaC) complex, in part by regulating the cell surface expression of the ENaC complex. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the transporter SLC4A7 . Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	Peptide affinity purified.
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Specificity	CFTR polyclonal antibody detects endogenous levels of CFTR protein.
BiowMW	168/69 kDa (Predicted band size)
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Synthetic peptide within C-terminal human CFTR.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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