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LC3A polyclonal antibody

LC3A polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neural Lineage Markers Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Immunocytochemistry Autophagy Primary Antibodies Astroglia Markers
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Applications	WB, IHC, ICC
Amount	50ul
Host	Rabbit
Item no.	BS90790-50
Targets	MAP1A;;MAP1LC3A
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	Q9H492(Human) Q91VR7(Mouse) Q6XVN8(Rat)
Application_all	WB:1:500 ICC:1:50-1:200 IHC:1:50-1:200
Background	Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	Peptide affinity purified
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Specificity	LC3A polyclonal antibody detects endogenous levels of LC3A protein.
BiowMW	14/16 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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