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Smad4 polyclonal antibody

Smad4 polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Targets for Rodent Neurosciences Antibodies Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Applications	WB, FC, IF, IHC, ICC
Amount	100ul
Host	Rabbit
Item no.	BS91255-100
Targets	SMAD4
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	Q13485(Human) P97471(Mouse) O70437(Rat)
Application_all	WB:1:1, 000-1:2, 000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100
Background	Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFbeta/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MADH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFbeta and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFbeta signaling by interfering with TGFbeta-mediated phosphorylation of other Smad family members.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	ProA affinity purified
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Specificity	Smad4 polyclonal antibody detects endogenous levels of Smad4 protein.
BiowMW	60 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	recombinant protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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