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Thioredoxin polyclonal antibody

Thioredoxin polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Antibodies Cell Biology Cell Status Flow Cytometry Western Blot Senescence Primary Antibodies
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Applications	WB, FC
Amount	50ul
Host	Rabbit
Item no.	BS91343-50
Targets	TRD ;; TXN
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	P10599(Human) P10639(Mouse) P11232(Rat)
Application_all	WB:1:1, 000-1:5, 000 FC:1:50-1:100
Background	Thioredoxin (Trx) is a redox protein that is found in several species, such as bacteria, plants and mammals, and contains a conserved active site, consisting of Trp-Cys-Gly-Pro-Cys. Trx has several biological functions. It acts as a hydrogen donor for ribonucleotide reductase, which is critical for DNA synthesis, and modulates the DNA-binding activity of several transcription factors, including NFkB, AP-1, p53, TFIIIC and glucocorticoid receptor. Trx also stimulates cell growth, is an inhibitor of apoptosis and plays a role in the protection against oxidative stress. Drugs that inhibit Trx have antitumor activity, suggesting that Trx is involved in a variety of human diseases, including cancer. TrxR is a ubiquitously expressed flavoprotein that catalyzes the NADPH-dependent reduction of Trx as well as several other oxidized cellular components.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	ProA affinity purified
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Specificity	Thioredoxin polyclonal antibody detects endogenous levels of Thioredoxin protein.
BiowMW	12 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	recombinant protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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