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PLK1 (Phospho-T210) polyclonal antibody

PLK1 (Phospho-T210) polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neural Lineage Markers Targets for Rodent Neurosciences Neural Development Antibodies Flow Cytometry Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies Progenitor Markers
Type	Antibody Primary
Specific against	Human
Applications	WB, FC, IF, ICC
Amount	100ul
Host	Rabbit
Item no.	BS94045-100
Targets	PBK ;;PLK1
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	P53350(Human)
Application_all	WB:1:500-1:1, 000 FC:1:10-1:50 ICC:1:10-1:50
Background	Plk (for polo-like kinase) encodes a serine/threonine kinase that is closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively. Polo and CDC5 both code for proteins that are involved in regulating the function of the mitotic spindle. Plk protein accumulates in the cell during the S and G2 phases of the cell cycle and both protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Plk expression is detectable in mitotically active tissues such as colon and placenta, as well as in tumors of various origins. It has also been suggested that Plk may serve as a marker of cell proliferation. The phosphorylation of mouse, rat and human Plk on Thr 210 enhances Plk catalytic activity.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	ProA affinity purified
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Specificity	PLK1 (Phospho-T210) polyclonal antibody detects endogenous levels of PLK1 protein only when phosphorylated at T210.
BiowMW	68 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Synthetic phospho-peptide corresponding to residues surrounding Thr210 of human PLK1.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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