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Cyclin E1 (Phospho-T77) polyclonal antibody

Cyclin E1 (Phospho-T77) polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neural Lineage Markers Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Proliferation Primary Antibodies
Type	Antibody Primary
Specific against	Human
Applications	WB, IF, IHC, ICC
Amount	100ul
Host	Rabbit
Item no.	BS94055-100
Targets	CCNE1;;PCNA
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	P24864(Human)
Application_all	WB:1:1, 000 ICC:1:50-1:200 IHC:1:50-1:200
Background	Cyclins were first identified in invertebrates as proteins that oscillate dramatically through the cell cycle. These proteins have been well conserved through evolution and play a critical role in regulation of cell division. cyclin E, along with the three cyclin D proteins and cyclin C, has been shown to represent a putative G1 cyclin on the basis of its cyclic pattern of mRNA expression, with maximal levels being detected near the G1/S boundary. cyclin E has been found to be associated with the transcription factor E2F in a temporally regulated manner. The cyclin E/E2F complex is detected primarily during the G1 phase of the cell cycle and decreases as cells enter S phase. E2F is known to be a critical transcription factor for expression of several S phase specific proteins.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	ProA affinity purified
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Specificity	Cyclin E1 (Phospho-T77) polyclonal antibody detects endogenous levels of Cyclin E1 protein only when phosphorylated at T77.
BiowMW	48 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Synthetic phospho-peptide corresponding to residues surrounding Thr77 of human Cyclin E1.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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