Comparison

AIRE-1 Polyclonal Antibody

Item no. BT-AP00312-50ul
Manufacturer Bioassay Technology Laboratory
Amount 50 ul
Category
Type Antibody Polyclonal
Applications WB, IF, ELISA
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias AIRE; APECED; Autoimmune regulator; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; APECED protein
Available
Ab type
Primary antibody
Background
AIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein (autoimmune regulator) plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).
Clonality
Polyclonal
Concentration
1 mg/ml
Immunogen
The antiserum was produced against synthesized peptide derived from human AIRE. AA range:91-140
MolecularWeight_Da
57727
Reactivity
Human; Mouse
Storage Stability
-20°C for one year

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ul
Available: In stock
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