Comparison

Cleaved-Factor X/ Factor X LC (A41) Polyclonal Antibody

Item no. BT-AP01923-100ul
Manufacturer Bioassay Technology Laboratory
Amount 100 ul
Category
Type Antibody Polyclonal
Applications WB, ELISA
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias F10; Coagulation factor X; Stuart factor; Stuart-Prower factor
Available
Ab type
Primary antibody
Background
F10 encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides.
Clonality
Polyclonal
Concentration
1 mg/ml
Immunogen
The antiserum was produced against synthesized peptide derived from human FA10. AA range:22-71
MolecularWeight_Da
54732
Reactivity
Human
Storage Stability
-20°C for one year

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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