Comparison

COL25A1 Polyclonal Antibody

Item no. BT-AP02079-50ul
Manufacturer Bioassay Technology Laboratory
Amount 50 ul
Category
Type Antibody Polyclonal
Applications WB, ELISA
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias COL25A1
Available
Ab type
Primary antibody
Background
COL25A1 (collagen type XXV alpha 1 chain) encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for COL25A1.
Clonality
Polyclonal
Concentration
1 mg/ml
Immunogen
Synthetic peptide from human protein at AA range: 101-150
MolecularWeight_Da
64771
Reactivity
Human; Mouse
Storage Stability
-20°C for one year

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ul
Available: In stock
available

Delivery expected until 7/17/2025 

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close