Comparison

Cortactin (Acetyl Lys235) Polyclonal Antibody

Item no. BT-AP02136-50ul
Manufacturer Bioassay Technology Laboratory
Amount 50 ul
Category
Type Antibody Polyclonal
Applications WB, ELISA
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CTTN; EMS1; Src substrate cortactin; Amplaxin; Oncogene EMS1
Available
Ab type
Primary antibody
Background
CTTN is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. Cortactin is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, cortactin is degraded in a caspase-dependent manner. The aberrant regulation of CTTN contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for CTTN.
Clonality
Polyclonal
Concentration
1 mg/ml
Immunogen
Synthesized acetyl-peptide derived from the Internal region of human Cortactin around the acetylation site of K235.
MolecularWeight_Da
61636
Reactivity
Human; Mouse; Rat
Storage Stability
-20°C for one year

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ul
Available: In stock
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