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GLUL polyclonal antibody

GLUL polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot Primary Antibodies Oligodendrocyte Markers
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Applications	WB, FC, IP, IHC
Amount	50ul
Host	Rabbit
Item no.	BZ00935-50
Targets	GLUL
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	P15104
Application_all	WB: 1:500-1:2000 IHC: 1:50-1:200 IP/FC: 1:50
Background	Glutamine synthetase (GI Syn) forms a homooctamer that serves as a catalyst for the amination of glutamic acid to form glutamine. This enzyme is a marker for astrocytes, which serve as the primary site of conversion of glutamic acid to glutamine in the brain. Induction of glutamine synthetase is seen upon astrocyte cell contact with neurons. Elevated expression of glutamine synthetase in glial cells has been shown to protect neurons from degeneration due to excess glutamate. Glutamine synthetase is also present in the liver and is involved in nitrogen homeostasis. Overexpression of glutamine synthetase has been shown in primary liver cancers, indicating a potential role for glutamine synthetase in hepatocyte transformation.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage And Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	Glutamine Synthetase Antibody detects endogenous levels of total Glutamine Synthetase.
BiowMW	ca. 49 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	A synthesized peptide derived from human Glutamine Synthetase.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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