Comparison

ITGAM Monoclonal Antibody,PE Conjugated

Item no. CSB-MA056993
Manufacturer Cusabio
Amount 100 ul
Category
Type Antibody Monoclonal
Format Liquid
Applications FC, IF, ELISA
Clone 20D2
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1
Conjugate/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Available
Manufacturer - Type
Hybridoma Monoclonal Antibody
Manufacturer - Targets
ITGAM
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen Species
Human
Immunogen
Recombinant Protein
Dilution
IF:1:100-1:200
Buffer
Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Purification Method
Affinity purified
General Research Areas
Signal Transduction
Initial Research Areas
Signal Transduction
Relevance
4AM216 reacts with CD11b, a member of the integrin a chain family with 165 kDa MW. which is expressed on NK cells, monocytes, granulocytes and subsets of T and B cells. It associates with CD18 to form CD11b/CD18 complex .The cellular function of CD11b is on neutrophil and monocyte interactions with stimulated endothelium, Phagocytosis of iC3b or IgG coated particles as a receptor, Chemotaxis and apoptosis.
* CD11b is absent in Leukocyte Adhesion Deficiency (LAD-1) patients who have major problems with bacterial infections.This clone is cross reactive with non-human primate.1. Ling NR , et al., eds. (1987) Leucocyte Typing , III : White Cell Differentiation Antigens, Oxford University Press, New York. 303-3342. Petty HR nd Todd RF. (1996) Immunol. Today 17:2093. Springer TA (1994) Cell 76:3014. Stewart M et al (1995) Curr Opin Cell Biol 7:690
Antigen Species
Human
Antigen
Recombinant Protein
Clonality
Monoclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
available

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