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BRAP Monoclonal Antibody

BRAP Monoclonal Antibody

Item no.	CSB-MA097714
Manufacturer	Cusabio
Amount	100 ul
Category	Oncology Antibodies By Cell Type Carcinoma Cell Biology Cytoskeleton Western Blot ELISA Primary Antibodies By Organ Breast Cancer small GTPases Ras Subfamily Rap Subfamily
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ELISA
Clone	20F7
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	3010002G07Rik; BRAP2; BRCA1 associated protein; EC 6.3.2.; Galectin 2 binding protein; IMP; Impedes mitogenic signal propagation; Renal carcinoma antigen NY REN 63; RING finger protein 52; RNF52; zgc:92894.
Similar products	RNF52, BRAP2, Impedes mitogenic signal propagation, RING finger protein 52, IMP, EC 6.3.2., BRCA1 associated protein, 3010002G07Rik, Galectin 2 binding protein, Renal carcinoma antigen NY REN 63, zgc:92894.
Available
Manufacturer - Type	Hybridoma Monoclonal Antibody
Manufacturer - Targets	BRAP
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen Species	Human
Immunogen	Purified recombinant human BRAP protein fragments expressed in E.coli.
Dilution	WB:1:500-1:5000
Buffer	Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Purification Method	Affinity purified
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Relevance	Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
Antigen Species	Human
Antigen	Purified recombinant human BRAP protein fragments expressed in E.coli.
Clonality	Monoclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/2/2025

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