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CBR1 Monoclonal Antibody

CBR1 Monoclonal Antibody

Item no.	CSB-MA106885
Manufacturer	Cusabio
Amount	100 ul
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Western Blot ELISA Immunocytochemistry Enzymes Prostaglandin Synthases Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ICC, ELISA
Clone	1E10
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	15 hydroxyprostaglandin dehydrogenase [NADP+]; 15-hydroxyprostaglandin dehydrogenase [NADP+]; Carbonyl reductase [NADPH] 1; Carbonyl Reductase 1; CBR 1; CBR1; CBR1_HUMAN; CRN; NADPH dependent carbonyl reductase 1; NADPH-dependent carbonyl reductase 1;
Similar products	CBR1, CRN, Carbonyl reductase [NADPH] 1, NADPH-dependent carbonyl reductase 1, 15 hydroxyprostaglandin dehydrogenase [NADP+], 15-hydroxyprostaglandin dehydrogenase [NADP+], Carbonyl Reductase 1, CBR 1, NADPH dependent carbonyl reductase 1, CBR1_HUMAN
Available
Manufacturer - Type	Hybridoma Monoclonal Antibody
Manufacturer - Targets	CBR1
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	15 hydroxyprostaglandin dehydrogenase [NADP+]; 15-hydroxyprostaglandin dehydrogenase [NADP+]; Carbonyl reductase [NADPH] 1; Carbonyl Reductase 1; CBR 1; CBR1; CBR1_HUMAN; CRN; NADPH dependent carbonyl reductase 1; NADPH-dependent carbonyl reductase 1;
Immunogen Species	Human
Immunogen	Purified recombinant human CBR1 protein fragments expressed in E.coli
Dilution	WB:1:500-1:5000, ICC:1:50-1:200
Buffer	Purified mouse monoclonal in PBS(pH 7.4)containing with 0.2% sodium azide, 50% glycerol.
Purification Method	Affinity purified
General Research Areas	Signal Transduction
Initial Research Areas	Signal Transduction
Relevance	NADPH-dependent reductase with broad substrate specificity.Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics.Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha.Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates.Catalyzes the reduction of S-nitrosoglutathione.
Antigen Species	Human
Antigen	Purified recombinant human CBR1 protein fragments expressed in E.coli
Clonality	Monoclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/9/2025

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