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SMAD2 Monoclonal Antibody

SMAD2 Monoclonal Antibody

Item no.	CSB-MA913719
Manufacturer	Cusabio
Amount	100 ul
Category	Neuroscience Neural Lineage Markers Antibodies Western Blot ELISA Immunocytochemistry Primary Antibodies Neurodegeneration Markers
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ICC, ELISA
Clone	2D9
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	hMAD 2; hMAD-2; hSMAD2; JV18 1; JV18; JV18; JV18-1; JV181; MAD; MAD; MAD homolog 2; MAD Related Protein 2; Mad-related protein 2; MADH2; MADR2; MGC22139; MGC34440; Mothers Against Decapentaplegic Homolog 2; Mothers Against Decapentaplegic Homolog 2;
Similar products	MAD, JV18-1, MADH2, hSMAD2, hMAD-2, JV18, MADR2, MGC22139, MGC34440, hMAD 2, JV18 1, JV181, MAD Related Protein 2, Mothers Against Decapentaplegic Homolog 2, MAD homolog 2, Mad-related protein 2
Available
Manufacturer - Type	Hybridoma Monoclonal Antibody
Manufacturer - Targets	SMAD2
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen Species	Human
Immunogen	Purified recombinant human SMAD2 protein fragments expressed in E.coli.
Dilution	WB:1:500-1:5000, ICC:1:50-1:200
Buffer	Ascites
Purification Method	Affinity purified
General Research Areas	Signal Transduction
Initial Research Areas	Signal Transduction
Relevance	Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases.Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription.May act as a tumor suppressor in colorectal carcinoma.Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Antigen Species	Human
Antigen	Purified recombinant human SMAD2 protein fragments expressed in E.coli.
Clonality	Monoclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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CSB-MA913719-datasheet.pdf

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Amount: 100 ul

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Delivery expected until 8/28/2025

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