RFX2 Antibody

RFX2

DNA-binding protein RFX2 antibody; HLA class II regulatory factor RFX2 antibody; regulatory factor X 2 (influences HLA class II expression) antibody; Regulatory factor X 2 antibody; regulatory factor X2 antibody; RFX2 antibody; RFX2_HUMAN antibody; trans acting regulatory factor 2 antibody

Synthesized peptide derived from internal of human RFX2.

a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites.

Reith W., Mol. Cell. Biol. 14:1230-1244(1994).
Sjoeblom T., Science 314:268-274(2006).

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Epigenetics and Nuclear Signaling

Synthesized peptide derived from internal of Human RFX2.