KCNA5 Antibody

Polyclonal Antibody

KCNA5

ATFB7 antibody, cardiac potassium channel antibody, HCK1 antibody, HK2 antibody, HPCN1 antibody, insulinoma and islet potassium channel antibody, KCNA5 antibody, KCNA5_HUMAN antibody, KV1.5 antibody, PCN1 antibody, potassium channel 1 antibody, Potassium channel, insulinoma and islet cell antibody, Potassium channel, voltage-gated, shaker-related subfamily, member 5 antibody, Potassium voltage gated channel subfamily A member 5 antibody, Potassium voltage-gated channel subfamily A member 5 antibody, Voltage-gated potassium channel HK2 antibody, voltage-gated potassium channel protein Kv1.5 antibody, Voltage-gated potassium channel subunit Kv1.5 antibody

Synthesized peptide derived from internal of human KCNA5.

Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. This channel displays rapid activation and slow inactivation. May play a role in regulating the secretion of insulin in normal pancreatic islets. Isoform 2 exhibits a voltage-dependent recovery from inactivation and an excessive cumulative inactivation.

Tamkun M.M., FASEB J. 5:331-337(1991).
Philipson L.H., Proc. Natl. Acad. Sci. U.S.A. 88:53-57(1991).
Curran M.E., Genomics 12:729-737(1992).

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Cardiovascular

Synthesized peptide derived from internal of Human KCNA5.