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IRS1 (Ab-312) Antibody

IRS1 (Ab-312) Antibody

Item no.	CSB-PA143388
Manufacturer	Cusabio
Amount	100 ul
Category	Oncology Neuroscience Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Immunohistochemistry Western Blot ELISA Immunofluorescence Endocrine Regulation of Lipid Metabolism Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	HIRS 1 antibody,HIRS1 antibody,Insulin receptor substrate 1 antibody,IRS 1 antibody,IRS-1 antibody,IRS1 antibody,IRS1_HUMAN antibody,OTTHUMP00000164234 antibody
Similar products	IRS-1, IRS1, Insulin receptor substrate-1
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB, IHC, IF; WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500
Manufacturer - Targets	IRS1
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen Species	Human
Immunogen	Synthesized non-phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 312 (A-T-S(p)-P-A).
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:3000 IHC:1:50-1:100 IF:1:100-1:500
Background	May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit By similarity. Araki E., Diabetes 42:1041-1054(1993). Nishiyama M., Biochem. Biophys. Res. Commun. 183:280-285(1992). The MGC Project Team, Genome Res. 14:2121-2127(2004)
Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
General Research Areas	Tags & Cell Markers
Initial Research Areas	Tags & Cell Markers
Antigen Species	Human
Antigen	Synthesized non-phosphopeptide derived from Human IRS-1 around the phosphorylation site of serine 312 (A-T-S(p)-P-A).
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/29/2026

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