KRT5 Antibody

Polyclonal Antibody

KRT5

58 kDa cytokeratin antibody, CK-5 antibody, CK5 antibody, Cytokeratin-5 antibody, Cytokeratin5 antibody, DDD antibody, DDD1 antibody, EBS2 antibody, epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types antibody, K2C5_HUMAN antibody, K5 antibody, keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types) antibody, Keratin 5 antibody, Keratin antibody, keratin complex 2, basic, gene 5 antibody, keratin, type II cytoskeletal 5 antibody, Keratin-5 antibody, Keratin5 antibody, KRT 5 antibody, Krt5 antibody, KRT5A antibody, type II cytoskeletal 5 antibody, Type-II keratin Kb5 antibody

Synthesized peptide derived from human Keratin 5.

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Bettina Peters, Mol. Biol. Cell, Jun 2001, 12: 1775.
J Casatorres, J. Biol. Chem., Aug 1994, 269: 20489 - 20496.
Karin M???er-Decker, Am. J. Pathol., Feb 2005, 166: 575 - 584.
Angel Ram???z, Genetics, May 2001, 158: 341.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Signal Transduction

Synthesized peptide derived from Human Keratin 5.