MAEA Antibody

Polyclonal Antibody

MAEA

1110030D19Rik antibody, Cell proliferation inducing gene 5 protein antibody, Cell proliferation-inducing gene 5 protein antibody, EMLP antibody, EMP antibody, Erythroblast macrophage protein antibody, GID complex subunit 9 FYV10 homolog antibody, GID9 antibody, HLC 10 antibody, HLC-10 antibody, HLC10 antibody, Human lung cancer oncogene 10 protein antibody, Lung cancer related protein 10 antibody, Macrophage erythroblast attacher antibody, MAEA antibody, MAEA_HUMAN antibody, MGC93683 antibody, PIG5 antibody, Proliferation inducing gene 5 antibody

Synthesized peptide derived from internal of human MAEA.

Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages, This MAEA-mediated contact inhibits erythroid cells apoptosis. Participates to erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.

Ota T., Nat. Genet. 36:40-45(2004).
Hanspal M., Blood 92:2940-2950(1998).
Bala S., Biochem. Biophys. Res. Commun. 342:1040-1048(2006).

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunology

Synthesized peptide derived from internal of Human MAEA.