FASLG Antibody

FASLG

ALPS1B antibody; Apoptosis (APO 1) antigen ligand 1 antibody; Apoptosis antigen ligand 1 antibody; Apoptosis antigen ligand antibody; APT1LG1 antibody; APTL antibody; CD178 antibody; CD178 antigen antibody; CD95 ligand antibody; CD95-L antibody; CD95L antibody; CD95L protein antibody; Fas antigen ligand antibody; Fas L antibody; Fas ligand (TNF superfamily member 6) antibody; Fas ligand antibody; FASL antibody; Fasl Fas ligand (TNF superfamily member 6) antibody; FASLG antibody; Generalized lymphoproliferative disease antibody; Gld antibody; soluble form antibody; TNFL6_HUMAN antibody; TNFSF6 antibody; Tumor necrosis factor (ligand) superfamily member 6 antibody; Tumor necrosis factor ligand superfamily member 6 antibody

Synthesized peptide derived from internal of human FAS ligand.

Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition.

Alderson M., J. Exp. Med. 181:71-77(1995).
Takahashi T., Int. Immunol. 6:1567-1574(1994).
Gregory S.G., ure 441:315-321(2006).

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Cell Biology

Synthesized peptide derived from internal of Human FAS ligand.