RAD18 Antibody

Polyclonal Antibody

RAD18

2810024C04Rik antibody, DNA repair protein rad18 antibody, E3 ubiquitin-protein ligase RAD18 antibody, EC 6.3.2.- antibody, hHR 18 antibody, hHR18 antibody, hRAD 18 antibody, hRAD18 antibody, MGC156682 antibody, Postreplication repair E3 ubiquitin-protein ligase RAD18 antibody, Postreplication repair protein hRAD18p antibody, Postreplication repair protein RAD18 antibody, RAD 18 antibody, RAD18 antibody, RAD18 homolog (S. cerevisiae) antibody, RAD18 homolog antibody, RAD18 S. cerevisiae homolog antibody, RAD18 S. cerevisiae homolog of antibody, RAD18 transcript variant antibody, RAD18_HUMAN antibody, Rad18sc antibody, Radiation sensitivity protein 18 antibody, RING finger protein 73 antibody, RNF 73 antibody, RNF73 antibody, Structural maintenance of chromosomes protein 6 antibody, YCR066W antibody, YCR66W antibody

Synthesized peptide derived from internal of human RAD18.

E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.

Tateishi S., Proc. Natl. Acad. Sci. U.S.A. 97:7927-7932(2000).
Xin H., Nucleic Acids Res. 28:2847-2854(2000).
Muzny D.M., Nature 440:1194-1198(2006).

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Epigenetics and Nuclear Signaling

Synthesized peptide derived from internal of Human RAD18.