KCNJ16 (Ab-416) Antibody

Polyclonal Antibody

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Synthesized non-phosphopeptide derived from human Kir5.

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance.

Liu Y., Cytogenet. Cell Genet. 90:60-63(2000).
Derst C., FEBS Lett. 491:305-311(2001).

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Neuroscience

Synthesized non-phosphopeptide derived from Human Kir5.