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NACC1 Antibody

NACC1 Antibody

Item no.	CSB-PA283286
Manufacturer	Cusabio
Amount	100 ul
Category	Neuroscience Metabolism Cholesterol & Lipid Metabolism Neural Development Antibodies Western Blot ELISA Enzymes Fatty Acid Synthesis Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BEND8 antibody; BTB Domain Containing 14B antibody; BTB/POZ domain-containing protein 14B antibody; btbd14b antibody; FLJ37383 antibody; NAC-1 antibody; NAC1 antibody; Nacc1 antibody; NACC1_HUMAN antibody; Nucleus accumbens-associated protein 1 antibody
Similar products	BTBD14B, NACC1, BEND8, FLJ37383, NAC-1
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	NACC1
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	BEND8 antibody; BTB Domain Containing 14B antibody; BTB/POZ domain-containing protein 14B antibody; btbd14b antibody; FLJ37383 antibody; NAC-1 antibody; NAC1 antibody; Nacc1 antibody; NACC1_HUMAN antibody; Nucleus accumbens-associated protein 1 antibody
Immunogen Species	Human
Immunogen	Peptide sequence around aa.519ca.523(A-G-P-S-A) derived from Human NAC1
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:1000
Background	Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines. ", A BTB/POZ protein, NAC-1, is related to tumor recurrence and is essential for tumor growth and survival.", Nakayama K., Nakayama N., Davidson B., et al. Proc. Natl. Acad. Sci. U.S.A. 103:18739-18744(2006) ", NAC-1 controls cell growth and survival by repressing transcription of Gadd45GIP1, a candidate tumor suppressor.", Nakayama K., Nakayama N., Wang T.-L., Shih I.-M. Cancer Res. 67:8058-8064(2007)
Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugateds. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	Peptide sequence around aa.519~523(A-G-P-S-A) derived from Human NAC1
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/2/2025

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