GTF2H2 Antibody

GTF2H2

Basic transcription factor 2 44 kDa subunit antibody; BTF2 antibody; BTF2 p44 antibody; BTF2-p44 antibody; BTF2P44 antibody; General transcription factor IIH antibody; General transcription factor IIH polypeptide 2 antibody; General transcription factor IIH subunit 2 antibody; General transcription factor IIH; polypeptide 2; 44kDa antibody; Gtf2h2 antibody; MGC102806 antibody; p44 antibody; T BTF2P44 antibody; T-BTF2P44 antibody; TF2H2_HUMAN antibody; TFIIH antibody; TFIIH basal transcription factor complex p44 subunit antibody

Synthesized peptide derived from N-terminal of human TF2H2.

Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter.

Humbert S., EMBO J. 13:2393-2398(1994).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
van der Steege G., Eur. J. Hum. Genet. 3:87-95(1995).

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Epigenetics and Nuclear Signaling

Synthesized peptide derived from N-terminal of Human TF2H2.