SERPIND1 Antibody

Polyclonal Antibody

SERPIND1

D22S673 antibody, HC II antibody, HC-II antibody, HC2 antibody, HCF2 antibody, HEP2_HUMAN antibody, Heparin cofactor 2 antibody, Heparin cofactor II antibody, HLS2 antibody, Leuserpin 2 antibody, LS2 antibody, Protease inhibitor leuserpin 2 antibody, Protease inhibitor leuserpin-2 antibody, serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1 antibody, Serpin D1 antibody, serpin peptidase inhibitor, clade D (heparin cofactor), member 1 antibody, SERPIND1 antibody, THPH10 antibody

Synthesized peptide derived from internal of human Heparin Cofactor II.

Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.

Blinder M.A., Biochemistry 27:752-759(1988).
Herzog R., Biochemistry 30:1350-1357(1991).
Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Cardiovascular

Synthesized peptide derived from internal of Human Heparin Cofactor II.