TRAF4 Antibody

TRAF4

CART 1 antibody; CART1 antibody; cysteine rich domain associated with ring and TRAF domain antibody; Cysteine rich domain associated with RING and Traf domains protein 1 antibody; Cysteine-rich domain associated with RING and Traf domains protein 1 antibody; Malignant 62 antibody; Metastatic lymph node gene 62 protein antibody; MLN 62 antibody; MLN62 antibody; RING finger protein 83 antibody; RNF 83 antibody; RNF83 antibody; TNF receptor associated factor 4 antibody; TNF receptor-associated factor 4 antibody; TRAF 4 antibody; Traf4 antibody; TRAF4_HUMAN antibody; tumor necrosis receptor-associated factor 4A antibody

Synthesized peptide derived from internal of human TRAF4.

Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract By similarity. Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions.

Tomasetto C.L., Genomics 28:367-376(1995).
Miller H.G., Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
Cai C.L., Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Cell Biology

Synthesized peptide derived from internal of Human TRAF4.