KCNJ4 Antibody

KCNJ4

Hippocampal inward rectifier antibody; Hippocampal inward rectifier potassium channel antibody; HIR antibody; HIRK2 antibody; HRK1 antibody; Inward rectifier K(+) channel Kir2.3 antibody; Inward rectifier K+ channel Kir2.3 antibody; Inward rectifier potassium channel 4 antibody; Inward rectifier potassium channel Kir 2.3 antibody; inwardly rectifying subfamily J member 4 antibody; IRK-3 antibody; IRK3 antibody; IRK4_HUMAN antibody; KCNJ 4 antibody; Kcnj4 antibody; Kir2.3 antibody; MGC142066 antibody; MGC142068 antibody; OTTHUMP00000028922 antibody; Potassium channel antibody; Potassium channel inwardly rectifying subfamily J member 4 antibody; Potassium inwardly rectifying channel J4 antibody; Potassium inwardly rectifying channel subfamily J member 4 antibody

Synthesized peptide derived from internal of human KCNJ4.

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium By similarity.

Perier F., Proc. Natl. Acad. Sci. U.S.A. 91:6240-6244(1994).
Tang W., FEBS Lett. 348:239-243(1994).
Makhina E.N., J. Biol. Chem. 269:20468-20474(1994).

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Neuroscience

Synthesized peptide derived from internal of Human KCNJ4.