EFNA3 Antibody

EFNA3

EFL 2 antibody; EFL-2 antibody; EFL2 antibody; EFN A3 antibody; EFNA 3 antibody; Efna3 antibody; EFNA3_HUMAN antibody; EHK1 L antibody; EHK1 ligand antibody; EHK1-L antibody; EHK1L antibody; EPH related receptor tyrosine kinase ligand 3 antibody; EPH-related receptor tyrosine kinase ligand 3 antibody; Ephrin-A3 antibody; EphrinA3 antibody; EPLG 3 antibody; EPLG3 antibody; LERK 3 antibody; LERK-3 antibody; LERK3 antibody; Ligand of eph related kinase 3 antibody

Synthesized peptide derived from C-terminal of human EFNA3.

Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling By similarity.

Kozlosky C.J., Oncogene 10:299-306(1995).
Davis S., Science 266:816-819(1994).
Gregory S.G., Nature 441:315-321(2006).

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Cardiovascular

Synthesized peptide derived from C-terminal of Human EFNA3.