CAD Polyclonal Antibody

CAD

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

IHC 1:40-1:200

Polyclonal

Polyclonal Antibodies