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CARD16 Polyclonal Antibody

CARD16 Polyclonal Antibody

Item no.	E-AB-17810-200
Manufacturer	Elabscience
Amount	200 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Neural Signaling Antibodies Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines Cell Status Apoptosis Immunohistochemistry Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CAR16, CARD only domain-containing protein 1, CARD only protein , CARD16, Caspase recruitment domain family, member 16, Caspase recruitment domain-containing protein 16, Caspase-1 dominant-negative inhibitor pseudo-ICE , Caspase-1 inhibitor COP, COP, COP1, Pseudo interleukin 1 beta converting enzyme, Pseudo interleukin-1 beta converting enzyme, Pseudo interleukin-1beta converting enzyme , PSEUDO-ICE
Similar products	CARD16, COP, COP1, Caspase recruitment domain-containing protein 16, CARD only domain-containing protein 1, Caspase-1 inhibitor COP, Pseudo interleukin-1 beta converting enzyme, PSEUDO-ICE, CARD only protein, member 16, CAR16, Caspase recruitment domain family, Caspase-1 dominant-negative inhibitor pseudo-ICE, Pseudo interleukin 1 beta converting enzyme, Pseudo interleukin-1beta converting enzyme
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	CARD16
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	23 kDa
Observed Molecular Weight	Refer to figures
Manufacturer - Research Areas	Cell Biology
Background	Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
Concentration	1.1 mg/mL
Buffer	PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method	Antigen affinity purification
Recommended Dilution	WB 1:500-1:2000; IHC 1:40-1:200
Abbreviation	CARD16
Clonality	Polyclonal
Immunogen	Synthetic peptide of human CARD16
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.