ZFAND5 Polyclonal Antibody

ZFAND5

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Refer to figures

Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

WB 1:500-1:2000; IHC 1:25-1:100

Polyclonal

Polyclonal Antibodies