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CRACR2A Polyclonal Antibody

CRACR2A Polyclonal Antibody

Item no.	E-AB-19269-60
Manufacturer	Elabscience
Amount	60 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Antibodies Immunohistochemistry ELISA Cardiovascular Research Myocardial Infarction Primary Antibodies
Type	Antibody Polyclonal
Applications	IHC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Calcium release-activated calcium channel regulator 2A, CRAC channel regulator 2A, CRACR2A, EF hand calcium binding domain 4B, EF hand calcium binding domain containing protein 4B, EF-hand calcium-binding domain-containing protein 4B, EFC4B, EFCAB 4B, Efcab4b, FLJ33805, MGC4266
Similar products	CRACR2A, EF-hand calcium-binding domain-containing protein 4B, Calcium release-activated calcium channel regulator 2A, FLJ33805, MGC4266, Efcab4b, EFC4B, CRAC channel regulator 2A, EF hand calcium binding domain 4B, EF hand calcium binding domain containing protein 4B, EFCAB 4B
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	CRACR2A
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Manufacturer - Research Areas	Signal transduction
Background	Ca2+-binding protein that plays a key role in store-operated Ca2+entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca2+resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex.
Concentration	0.84 mg/mL
Buffer	PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method	Antigen affinity purification
Recommended Dilution	IHC 1:50-1:200
Abbreviation	CRACR2A
Clonality	Polyclonal
Immunogen	Fusion protein of human CRACR2A
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.