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RBL2 Polyclonal Antibody

RBL2 Polyclonal Antibody

Item no.	E-AB-19324-200
Manufacturer	Elabscience
Amount	200 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Metabolism Diabetes Glucose Homeostasis Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Immunohistochemistry ELISA Senescence Cardiovascular Research Atherosclerosis Primary Antibodies Astrocytoma By Organ Bladder Cancer Head & Neck Cancer Brain Cancer Bone Cancer
Type	Antibody Polyclonal
Applications	IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	130 kDa retinoblastoma associated protein, 130 kDa retinoblastoma-associated protein, IB4, p130, PPAR-alpha-interacting complex protein 128, PRB2, Rb2, Rbl2, RBL2, RBR 2, RBR-2, RBR2, Retinoblastoma like 2, Retinoblastoma-like protein 2, Retinoblastoma-related protein 2, RIC128
Similar products	RBL2, Retinoblastoma-like protein 2, 130 kDa retinoblastoma-associated protein, Retinoblastoma-related protein 2, PRB2, Rbl2, RBR2, Rb2, 130 kDa retinoblastoma associated protein, p130, RBR 2, Retinoblastoma like 2, RBR-2, IB4, PPAR-alpha-interacting complex protein 128, RIC128
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	RBL2
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Manufacturer - Research Areas	Cancer, Cell Biology, Epigenetics and Nuclear Signaling
Background	Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.
Concentration	0.8 mg/mL
Buffer	PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method	Antigen affinity purification
Recommended Dilution	IHC 1:30-1:150
Abbreviation	RBL2
Clonality	Polyclonal
Immunogen	Synthetic peptide of human RBL2
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.