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CASP8 Polyclonal Antibody

CASP8 Polyclonal Antibody

Item no.	E-AB-19664-60
Manufacturer	Elabscience
Amount	60 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Cell Biology Cell Status Apoptosis Immunohistochemistry ELISA Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer Gastric Cancer Uterine, Ovarian & Cervical Cancer
Type	Antibody Polyclonal
Applications	IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ALPS2B, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein, Apoptotic cysteine protease, Apoptotic protease Mch-5, Apoptotic protease Mch5, CAP4, CASP-8, CASP8, CASP8, Caspase 8, Caspase 8 apoptosis related cysteine peptidase, Caspase-8 subunit p10, CED 3, FADD Like ICE, FADD-homologous ICE/CED-3-like protease, FADD-like ICE, FLICE, FLJ17672, ICE-like apoptotic protease 5, MACH alpha 1/2/3 protein, MACH, MACH beta 1/2/3/4 protein, MCH5, MGC78473, MORT1 associated ced 3 homolog, MORT1-associated CED-3 homolog, OTTHUMP00000163717, OTTHUMP00000163720, OTTHUMP00000163724, OTTHUMP00000163725, OTTHUMP00000165062, OTTHUMP00000165063, OTTHUMP00000165064, OTTHUMP00000206552, OTTHUMP00000206582
Similar products	CASP8, MCH5, Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, FADD-like ICE, ICE-like apoptotic protease 5, Caspase-8 subunit p10, CASP-8, FLICE, MACH, Caspase 8, OTTHUMP00000163724, OTTHUMP00000206582, ALPS2B, FLJ17672, MGC78473, FADD-homologous ICE/CED-3-like protease, OTTHUMP00000163720, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein, MORT1-associated CED-3 homolog, Apoptotic protease Mch5, Caspase 8 apoptosis related cysteine peptidase, CED 3, FADD Like ICE, MACH alpha 1/2/3 protein, MACH beta 1/2/3/4 protein, MORT1 associated ced 3 homolog, OTTHUMP00000163717, OTTHUMP00000163725, OTTHUMP00000165062, OTTHUMP00000165063, OTTHUMP00000165064, OTTHUMP00000206552
Shipping Condition	Cool pack
Available
Manufacturer - Category	Polyclonal Antibody
Shipping Temperature	Biological Ice Packs
Storage Conditions	-20°C for 12 months
Research Areas	Cancer, Cell Biology, Metabolism
Background	Caspase 8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3. It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. Caspase 8 Monoclonal Antibody can recognize pro- and cleaved-caspase 8.
Concentration	0.5 mg/mL
Buffer	PBS with 0.05% NaN3 and 40% Glycerol, pH 7.4
Purification Method	Antigen affinity purification
Recommended Dilution	IHC 1:30-1:150, ELISA 1:5000-1:10000
Clonality	Polyclonal
Immunogen	Synthetic peptide of human CASP8

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.