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AKT1 Monoclonal Antibody

AKT1 Monoclonal Antibody

Item no.	E-AB-22210-120
Manufacturer	Elabscience
Amount	120 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Neuroscience Aging & Neurological Disorders Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Monoclonal
Applications	WB
Clone	10D6
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	https://www.sciencedirect.com/science/article/pii/S0753332220310209
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	AKT 1, AKT, AKT1, AKT1, MGC99656, PKB, PKB-ALPHA, PRKBA, Protein Kinase B Alpha, Protein kinase B, Proto-oncogene c-Akt, RAC Alpha, RAC, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha
Similar products	AKT, AKT1, PKB, RAC, RAC-alpha serine/threonine-protein kinase, Protein kinase B, Proto-oncogene c-Akt, RAC-PK-alpha, MGC99656, PKB-ALPHA, PRKBA, AKT 1, Protein Kinase B Alpha, RAC Alpha
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	AKT1
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Observed Molecular Weight	60kDa
Research Areas	Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction
Background	The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery.
Concentration	1 mg/mL
Buffer	PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification Method	Protein A purification
Recommended Dilution	WB 1:1000-2000
Abbreviation	AKT1
Clonality	Monoclonal
Immunogen	Synthetic Peptide of AKT1
Category ID III	Monoclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.