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MCM3 Polyclonal Antibody

MCM3 Polyclonal Antibody

Item no.	E-AB-40230-20
Manufacturer	Elabscience
Amount	20 uL
Quantity options	100 uL 120 uL 20 uL 200 uL 25 uL 60 uL
Category	Oncology Neuroscience Metabolism Diabetes Glucose Homeostasis Regulation of Appetite Aging & Neurological Disorders Antibodies Cell Biology Cell Status Immunohistochemistry Proliferation Primary Antibodies By Organ Uterine, Ovarian & Cervical Cancer
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cervical cancer proto oncogene 5, DNA polymerase alpha holoenzyme associated P1, HCC 5, HCC5, hRlf beta subunit, Human cervical cancer proto oncogene 5, MCM 3, MGC1157, Minichromosome maintenance complex component 3, P1 h, P1 MCM3, P1.h, p102, Replication licensing factor beta subunit, <br />RLF beta subunit, RLFB
Similar products	p102, HCC5, MGC1157, P1.h, RLFB, hRlf beta subunit, Cervical cancer proto oncogene 5, DNA polymerase alpha holoenzyme associated P1, HCC 5, Human cervical cancer proto oncogene 5, MCM 3, Minichromosome maintenance complex component 3, P1 h, P1 MCM3, Replication licensing factor beta subunit, RLF beta subunit
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	MCM3
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	91, 96 kDa
Observed Molecular Weight	100 kDa
Manufacturer - Research Areas	Cancer, Epigenetics and Nuclear Signaling
Background	The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with mCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.
Concentration	1 mg/mL
Buffer	PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Purification Method	Antigen Affinity Purification
Recommended Dilution	WB 1:500-1:1000; IHC 1:50-1:200
Abbreviation	MCM3
Clonality	Polyclonal
Immunogen	Recombinant Human DNA replication licensing factor MCM3 protein
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.